Friday 16 March 2012

The Cushings

Have you ever been confused with the different Cushing's?
There are four types of Cushing's:
Cushing's Disease, Cushing's Syndrome, Cushing's triad and Cushing's reflex. (If you have more, do tell....)

  • Cushing's reflex/triad is not related to the syndrome and diseas and in order to know the disease, you need to know the syndrome.

  • Cushing's syndrome is a due to chronic high blood levels of cortisol or corticosteroids and it produces a constellation of symptoms and signs.
  • Cushing's disease is Cushing's syndrome that results from excessive pituiraty production of ACTH mostly due to a pituitary adenoma. Pituitary produces ACTH, remember.

  • Cushing's triad belongs to the raised intracranial hypertension. It's a triad so there are 3 signs: systemic hypertension, bradycardia and irregular respiration (cheyne's stokes)

Now, the Cushing's reflex is what is confusing me. I believe due to the raised ICP there is decreased blood perfusion and so it gives rise to the classic triad of Cushing's... but I need to make sure.

Any questions or any corrections please do inform.